The publications contained in this archive section are provided for historical purposes only. The views expressed in the publications are those of their respective authors and do not reflect the views of TME Pharma. TME Pharma disavows any obligation to update or correct the information contained in these publications.
Riecke K, Ludwig H, van Eijk L, Boyce M, Pickkers P, Macdougall I, Schwöbel F, Swinkels D.
Clinical Pharmacology, Efficacy, and Safety of the Anti-Hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94).
European Iron Club 2014, Verona
Presentation
Georgiev P, Lazaroiu M, Ocroteala L, Grudeva-Popova J, Gheorghita E, Vasilica M, Popescu S, Cucuianu A, Summo L, Schwoebel F, Riecke K, Ludwig H.
The Anti-Hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94) as Treatment of Anemia of Chronic Disease in Patients with Multiple Myeloma, Low Grade Lymphoma, and CLL: a Phase II pilot Study.
European Hematology Association 2014, Milan
Poster
Steurer M, Montillo M, Scarfò L, Mauro FR, Andel J, Wildner S, Trentin L, Janssens A, Burgstaller S, Kruschinski A, Dümmler T, Riecke K, Ghia P, Caligaris-Cappio F, Gobbi M.
Results from a Phase IIa Study of the Anti-CXCL12 Spiegelmer Olaptesed Pegol (NOX-A12) in Combination with Bendamustine/Rituximab in Patients with Chronic Lymphocytic Leukemia.
ASH 2014, San Francisco
Poster
Ludwig H, Weisel K, Petrucci MT, Leleu X, Cafro AM, Garderet L, Zojer N, Riecke K, Kruschinski A, Dümmler T, Foa R, Greil R, Yakoub-Agha I, Engelhardt M.
Final Results from the Phase IIa Study of the Anti-CXCL12 Spiegelmer Olaptesed Pegol (NOX-A12) in Combination with Bortezomib and Dexamethasone in Patients with Multiple Myeloma.
ASH 2014, San Francisco
Poster
Zboralski D, Vater A, Kruschinski A.
Comparison of Ibrutinib, Idelalisib and Olaptesed Pegol on the Immune Effector Function Mediated by Rituximab and Obinutuzumab.
ASH 2014, San Francisco
Poster
Georgiev P, Lazaroiu M, Ocroteala L, Grudeva-Popova J, Gheorghita E, Vasilica M, Popescu SM, Cucuianu A, Summo L, Schwoebel F, Riecke K, Ludwig H.
The anti-hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94) as treatment of anemia of chronic disease in patients with multiple myeloma, low grade lymphoma, and CLL: A phase II pilot study.
Cancer Research. 2014, 74, 3847.
read abstract on aacrjournals.org
van Eijk LT, John AS, Schwoebel F, Summo L, Vauléon S, Zöllner S, Laarakkers CM, Kox M, van der Hoeven JG, Swinkels DW, Riecke K, Pickkers P.
Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans.
Blood. 2014, 124(17), 2643-6.
read article on bloodjournal.org
Steinbicker AU.
Comment on van Eijk et al
A novel treatment of anemia of inflammation.
Blood. 2014, 124(17), 2618-19.
read comment on bloodjournal.org
Roccaro et al.
SDF-1 Inhibition Targets the Bone Marrow Niche for Cancer Therapy.
Cell Reports. 2014, 9(1), 118-28.
read article on cell.com
Purschke WG, Hoehlig K, Buchner K, Zboralski D, Schwoebel F, Vater A, Klussmann S.
Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes Sphingosine-1-Phosphate, a central mediator of angiogenesis.
Biochemical J. 2014, 462(1), 153-62.
read article on biochemj.org
Jerlhag E, Ivanoff L, Vater A, Engel JA.
Peripherally circulating ghrelin does not mediate alcohol-induced reward and alcohol intake in rodents.
Alcohol Clin Exp Res. 2014, 38(4), 959-68.
read article on wiley.com
Ehling J, Bartneck M, Wei X, Gremse F, Fech V, Möckel D, Baeck C, Hittatiya K, Eulberg D, Luedde T, Kiessling F, Trautwein C, Lammers T, Tacke F.
CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis.
Gut. 2014, 63(12), 1960-71.
view PubMed abstract on ncbi.nlm.nih.gov
Baeck C, Wei X, Bartneck M, Fech V, Heymann F, Gassler N, Hittatiya K, Eulberg D, Luedde T, Trautwein C, Tacke F.
Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C+ macrophage infiltration in mice.
Hepatology. 2014,59(3), 1060-72.
read abstract on wiley.com
Yamamoto H, Qin Y, Achenbach J, Li C, Kijek J, Spahn CM, Nierhaus KH.
EF-G and EF4: translocation and back-translocation on the bacterial ribosome.
Nat Rev Microbiol. 2014, 12, 89-100.
read abstract on nature.com
Liu S-C, Alomran R, Chernikova SB, Lartey F, Stafford J, Jang T, Merchant M, Zboralski D, Zöllner S, Kruschinski A, Klussmann S, Recht L, Brown JM.
Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats.
Neuro-Oncology. 2014, 16(1), 21-28.
read article on oxfordjournals.org
Hoellenriegel J, Zboralski D, Maasch C, Rosin NY, Wierda WG, Keating MJ, Kruschinski A, Burger JA.
The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
Blood. 2014, 123(7), 1032-1039.
view abstract on hematologylibrary.org
Marasca R, Maffei R.
Comment on Hoellenriegel et al
NOX-A12: mobilizing CLL away from home.
Blood. 2014, 123(7), 952-953.
read comment on hematologylibrary.org